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 Statins Can Reduce The Risk For Coronary Problems | Heart Attack Symptoms

Statin therapy

holds great promise for reducing the incidence of major coronary events, coronary procedures, and stroke in high-risk patients. At present, this potential has not been fully realized, because many patients at heightened risk are not being treated with these drugs. Get The Facts About: Xerisan Synephrine Diet Pill

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There is a well documented under-use of statins in clinical practice. Statins have proven to be extremely safe in the vast majority of patients receiving them. Few significant side effects were observed in clinical trials, and post-marketing reports of adverse events have been very limited when considered in comparison to the very large number of persons safely receiving these drugs. Even so, these drugs are not entirely free of side effects, and as for all drugs, they should be used appropriately and judiciously. This advisory encourages the appropriate use of statins while pointing out the possibility of side effects in certain patients.

If statins are used with appropriate caution in these selected patients, the likelihood of developing clinically important myopathy should be substantially reduced.

 

Statins are powerful low-density lipoprotein (LDL)- lowering drugs that are widely used in clinical practice. Results from clinical trials with a mean duration of 5.4 years have demonstrated a decrease in CHD and total mortality, reductions in myocardial infarctions, revascularization procedures, stroke, and peripheral vascular disease (2– 8). These trials documented a benefit in both men and women, primarily in middle-aged and older persons treated in the setting of either primary or secondary prevention. More than 50,000 individuals have been randomized to either a placebo or statin in these trials, and no serious  morbidity or increase in mortality was observed in the drug treatment groups. These agents reduce the risk of essentially every clinical manifestation of the atherosclerotic process; they are easy to administer, with good patient acceptance. There are very few drug to drug interactions. Although the experience with the safety of statin therapy outside of clinical trials has not been fully reported, it is reasonable to suspect that the incidence of side effects may be higher in clinical situations where patients are not monitored as closely as they are in clinical trials.

Source: National Institute Of Health

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